Practice setting and hospital outpatient ownership status had the strongest associations with the adoption of the first three biosimilars launched in Medicare, according to a recent study published in JAMA Network Open. By analyzing use of the biosimilar versions of filgrastim and infliximab among more than 40,000 Medicare fee-for service beneficiaries, the study found that patient and physician characteristics did not strongly correlate with whether a patient received a biosimilar. While the setting of administration had the greatest association with biosimilar uptake, the direction of association differed by drug class. For instance, a patient in a hospital outpatient setting was 16 percentage points less likely to receive a filgrastim biosimilar than a patient in an office setting, but 3 percentage points more likely to receive an infliximab biosimilar.

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