CGRPs for Migraine Play Role in Value-Based Contracting

Despite a slew of new branded therapies for acute migraine treatment and migraine prevention, many of which target calcitonin gene-related peptide (CGRP) receptors, health plans and PBMs continue to rely mainly on generic triptans for acute migraine treatment and generic beta-blockers, antiepileptics and tricyclic antidepressants for migraine prevention, drug benefits experts say.

Still, the new drugs available, particularly the CGRP receptor antagonists, provide options for patients whose migraines aren’t adequately controlled by traditional therapies, says Mesfin Tegenu, CEO and chairman of RxParadigm, a pharmacy benefit cost management start-up focused on providing tools and transparency. The CGRPs may also prompt more value-based contracting in the migraine class, he says.

© 2022 MMIT
Freelance Reporter

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