Study Finds Multistakeholder Benefits to NCCN-Supported Approach to Breast Cancer

Various randomized controlled trials have found that hypofractionated whole breast irradiation (HF-WBI) for certain patients with early-stage breast cancer is not only equivalent to standard radiation therapy for local control of the disease but also is less toxic, has better patient adherence and provides improved patient well-being. Those results led the National Comprehensive Cancer Network (NCCN) to add the approach to its guidelines. But while hypofractionation can benefit patients, providers and health plans, there has been slow uptake of it. A recent study found that putting clinical pathways in place that include mandating HF-WBI’s use improved compliance with the guidelines.

One retrospective study found that health plans spent $6,375 less for HF-WBI than they spent on conventional whole breast irradiation, and patients saved about $140 aside from travel-related costs.

© 2025 MMIT
Angela Maas

Angela Maas

Angela has an extensive background of editing, reporting and writing for trade and consumer publications. She has written Radar on Specialty Pharmacy since she joined AIS Health in 2005 and has broad knowledge of the various issues at play within the space. She also has written for Spotlight on Market Access since its 2017 launch. Before joining AIS Health, she was managing editor at Employee Benefit News and Employee Benefit News Canada and managing editor at Hem Aware (a hemophilia publication), Lupus Living and Momentum (a multiple sclerosis publication). She has a B.A. in English and an M.A. in British literature from Arizona State University.

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